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GlossaryMAPK pathway (Mitogen-Activated Protein Kinase pathway)

crucial cell signaling mechanism regulating growth, division, and stress response

The MAPK pathway, or Mitogen-Activated Protein Kinase pathway, is a crucial signaling mechanism in cells that helps regulate various activities such as growth, division, and response to stress. It involves a series of proteins that communicate signals from the cell surface to the DNA in the nucleus, ultimately influencing gene expression and cellular behavior. This pathway is significant in many biological processes and is often studied in the context of diseases like cancer and conditions affecting hair growth, such as alopecia.

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Melatonin Regulates the Mitogen-Activated Protein Kinase Pathway via the CircMPP5-miR-211-MAPK3 Axis to Induce Secondary Hair Follicle Differentiation and Development in Newborn Cashmere Goat Kids

research Melatonin Regulates the Mitogen-Activated Protein Kinase Pathway via the CircMPP5-miR-211-MAPK3 Axis to Induce Secondary Hair Follicle Differentiation and Development in Newborn Cashmere Goat Kids

1 citations, October 2022 in “Research Square (Research Square)”

Melatonin helps improve Cashmere goat hair quality by promoting hair follicle growth through a specific cell signaling pathway.

Phosphatidic Acid Has Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells

research Phosphatidic Acid Has Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells

46 citations, August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology”

Phosphatidic acid may help hair grow by affecting cell growth pathways.

research LL-37 Stimulates the Functions of Adipose-Derived Stromal/Stem Cells via Early Growth Response 1 and the MAPK Pathway

53 citations, April 2016 in “Stem cell research & therapy”

LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.

research The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells

42 citations, February 2014 in “Stem Cells and Development”

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1

3 citations, July 2020 in “Frontiers in Cell and Developmental Biology”

Vitexin Compound 1 may help reduce skin aging caused by UVA light.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 122 upvotes 5 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.