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GlossaryJNK pathway (JNK signaling)

signaling cascade responding to stress, regulating inflammation and cell death

The JNK pathway, also known as the c-Jun N-terminal kinase pathway, is a signaling cascade within cells that responds to stress stimuli, such as UV radiation and inflammatory cytokines. It plays a crucial role in regulating various cellular processes, including inflammation, apoptosis (programmed cell death), and cell differentiation. This pathway is significant in understanding diseases like cancer and neurodegenerative disorders, as well as conditions affecting hair growth and alopecia.

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research Activin B Promotes BMSC-Mediated Cutaneous Wound Healing by Regulating Cell Migration via the JNK-ERK Signaling Pathway

45 citations, April 2013 in “Cell Transplantation”

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

research Activin B Promotes Epithelial Wound Healing In Vivo Through RhoA-JNK Signaling Pathway

38 citations, September 2011 in “PLOS ONE”

Activin B helps heal skin wounds and grow hair by activating a specific cell signaling pathway.

research Co-Opting Developmental Signaling Pathways to Promote Wound Healing

1 citations, January 2018 in “Recent clinical techniques, results, and research in wounds”

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways

research Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways

14 citations, July 2021 in “Biomolecules”

Centipeda minima extract helps hair grow by activating important growth signals and could be a promising hair loss treatment.

research Context-Dependent Effect of sPLA2-IIA Induced Proliferation on Murine Hair Follicle Stem Cells and Human Epithelial Cancer

13 citations, September 2019 in “EBioMedicine”

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

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community Physio-metabolic method (antiandrogen, minoxidil, leg training and cold)

in Treatments 309 upvotes 5 months ago

The method combines finasteride, minoxidil, intense leg exercises, and cold exposure to treat androgenetic alopecia. It aims to boost metabolism and reduce androgenic effects, enhancing hair growth.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 6 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.