learn Minoxidil
An essential vasodilator with some anti-androgenic effects, has excellent safety record
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5 / 18 resultslearn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn Cyproterone
a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor
learn Sulforaphane
compound from cruciferous vegetables has some mild effects on DHT
learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
Research
5 / 1000+ results
research A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors
The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.
research Penis Endocrinology
Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.
research Maternal Androgen Excess Induces Cardiac Hypertrophy and Left Ventricular Dysfunction in Female Mice Offspring
High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.
research Contribution of Androgens to Chronic Allograft Nephropathy Is Mediated by Dihydrotestosterone
Male hormones worsen kidney transplant damage, but blocking them helps.
research An Updated Etiology of Hair Loss and the New Cosmeceutical Paradigm in Therapy: Clearing the Big Eight Strikes
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
Community Join
5 / 1000+ resultscommunity Wanted to say that Derma rolling and Pumpkin seed oil helped my crown out.
Derma rolling, pumpkin seed oil, and daily massages helped regrow weak hairs on the crown. Nizoral shampoo and yoga also contributed to reducing scalp pain and stress.
community Reminder how little the average person knows about hair loss
How little the average person knows about hair loss and how it can be an unfairly stigmatized issue, even by people with little knowledge of it themselves. Some specific treatments that were discussed include finasteride, RU58841, dutasteride, minoxidil, pyritinol, dermarolling, and diet/lifestyle changes.
community Got a microscope camera. Here’s the difference between healthy and miniaturized hair
A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.
community Finasteride and natural topicals
A user reported hairline regrowth after two weeks on a treatment including finasteride, peppermint and rosemary oils, emu oil, magnesium oil spray, apple cider vinegar, and dermarolling, while avoiding shampoos and conditioners. They believe DHT contributes to hair loss but also suggest follicle fibrosis is an issue.
community You guys should check this out: the connection between cortisol, DHT, inflammation and fibrosis explained?
The conversation discusses the effectiveness of finasteride and microneedling for treating hair loss. The linked article is seen as an advertisement for these treatments.