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Glossary Dermal Condensate

cluster of specialized skin cells initiating hair follicle formation

Dermal condensate refers to a cluster of specialized cells in the skin's dermis layer that play a crucial role in the formation of hair follicles. These cells signal to the overlying epidermal cells to start the process of hair follicle development, making them essential for hair growth and regeneration.

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Research

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research Decision letter: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation

April 2018

This study found that fibroblast growth factor 20 (Fgf20) orchestrates the movement and behavior of dermal fibroblasts, directing their formation into dermal condensates during hair follicle development in mice.

research Author response: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation

1 citations , July 2018

In this study, Fgf20 was found to trigger movement and morphogenesis in dermal fibroblasts, facilitating dermal condensate formation essential for hair follicle development.

research Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals

130 citations , February 2005 in “Proceedings of the National Academy of Sciences”

This study found that differentiated cells of the corneal epithelium can be converted to hair and interfollicular epidermis through a multistep process involving dermal developmental signals.

research BMP2 and BMP7 play antagonistic roles in feather induction

88 citations , July 2008 in “Development”

This study shows that BMP2 and BMP7 play complex, necessary roles in feather development by regulating dermal condensation formation, with BMP7 acting early as a chemoattractant and BMP2 halting cell migration.

research The Historical Studies Underpinning the Concept of Hair Follicle Neogenesis

January 2022 in “Springer eBooks”

This review discusses the potential of the hair follicle dermis to direct hair development and explores concepts related to hair growth and androgenetic alopecia, without reporting new clinical results.

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community My 5 year hair loss journey on Min & Fin.

1220 upvotes 5 months ago

A user shared their 5-year experience using minoxidil and finasteride, noting significant hair improvements without side effects. Consistency, a positive mindset, and lifestyle changes like a healthier diet and better sleep were key to their success.

community 5 year Fin + topical Min progress, switch to Duta+Oral Min January 1st 2026.

in Progress Pictures 48 upvotes 8 months ago

The user shared their 5-year progress using finasteride and topical minoxidil for hair growth, noting initial success but recent thinning and side effects. They plan to switch to dutasteride and oral minoxidil, addressing low iron levels and monitoring potential side effects.

community People's ignorance on MPB is both frustrating and harmful to balding men and it's important to educate other balding men on Fin/Min/Dut (Discussion)

156 upvotes 1 year ago

Many are unaware of effective male pattern baldness treatments like finasteride and minoxidil, often opting for ineffective remedies. Educating others on proven treatments and potential side effects is crucial.

community The shedding caused by Minoxidil is one of the worst things. 2 months apart each picture

in Progress Pictures 290 upvotes 2 years ago

The conversation discusses the severe shedding caused by Minoxidil, with users sharing their experiences and outcomes. Some report eventual regrowth, while others see no improvement or worsening hair loss.

community Finasteride won’t make all your problems go away

in Finasteride/Dutasteride 323 upvotes 2 years ago

A user shared that while finasteride improved their hair, it didn't solve all their insecurities, suggesting that self-acceptance is key. Others in the conversation expressed varying opinions, with some feeling that finasteride significantly boosted their confidence and quality of life, while others acknowledged it as a solution to hair loss but not a cure-all for other personal issues.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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