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      learn GT20029

      research compound made to degrade androgen receptors in scalp

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Sulforaphane

      compound from cruciferous vegetables has some mild effects on DHT

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community Androgen degraders for hair loss

      in Research/Science  60 upvotes 9 months ago
      The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

      community Fluridil degrades the androgen receptor.

      in Research/Science  11 upvotes 3 weeks ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

      community Does pyri/kx826 degrade in exposure to bathroom light?

      in Treatment  5 upvotes 10 months ago
      The conversation discusses concerns about RU58841 degrading when exposed to light and transferring pyri to a dark glass bottle to prevent this. The user keeps the pyri out for only two minutes before storing it in a dark place.

      community A concern regarding the upcoming androgen degrader drug GT20029

      in Chat  11 upvotes 5 months ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.