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Did you mean Cytokine receptor?

Glossary Cytokine receptor

protein on cell surface that binds signaling molecules

A cytokine receptor is a type of protein found on the surface of cells that binds to cytokines, which are signaling molecules that help regulate the immune system and inflammation. When a cytokine binds to its receptor, it triggers a series of cellular responses that can influence cell growth, differentiation, and immune responses. This interaction is crucial for coordinating the body's defense mechanisms and maintaining homeostasis.

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Research

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research Influence of interleukin‐1α on androgen receptor expression and cytokine secretion by cultured human dermal papilla cells

14 citations , September 2006 in “Experimental Dermatology”

This study suggests that interleukin-1 α influences dermal papilla cell activity by modifying androgen receptor expression and increasing the secretion of several growth factors and cytokines.

The Association of Cytosine-Adenine-Guanine Repeat Polymorphism in the Androgen Receptor Gene with Nodulocystic Acne in Egyptian Patients

research The association of cytosine-adenine-guanine repeat polymorphism in the androgen receptor gene with nodulocystic acne in Egyptian patients

June 2023 in “International Journal of Research in Dermatology”

In this study, Egyptian nodulocystic acne patients had significantly fewer CAG repeats in their androgen receptor gene compared to controls, which may influence acne development and suggest a role for antiandrogen therapy in treatment strategies.

research Interleukin‐1 family cytokines and soluble receptors in hidradenitis suppurativa

3 citations , September 2024 in “Experimental Dermatology”

This study found elevated levels of IL-18 and free IL-18 in hidradenitis suppurativa patients compared to healthy controls, suggesting these cytokines may serve as novel biomarkers for disease activity, with correlations indicating their involvement in disease severity.

research Multimodal roles of transient receptor potential channel activation in inducing pathological tissue scarification

7 citations , August 2023 in “Frontiers in Immunology”

This review discusses the role of transient receptor potential channels in pathological scarification and suggests these channels as potential targets for its prevention and treatment, although it reports no new clinical findings.

research Cannabinoids and Their Receptors in Skin Diseases

1 citations , November 2023 in “International journal of molecular sciences”

This article highlights that while cannabinoids show potential for treating various skin conditions, current evidence is largely preclinical, with a need for comprehensive clinical trials to confirm these promising effects.

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Community Join

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community Dental Cavitations, Inflammatory Cytokines (RANTES/CCL5) and Hair Loss

2 months ago

Dental cavitations and their potential link to hair loss through systemic inflammation. The user experienced hair regrowth after dental surgery, suggesting a connection between oral health and hair loss, but this theory is not widely accepted or proven.

community The 2026 Breakthrough Pipeline: Top 5 Mind-Changing Hair Loss Treatments To Watch

6 days ago

New hair loss treatments include lab-grown hair cloning, scarless healing with verteporfin, GT20029 for receptor degradation, JAK inhibitors for follicle activation, and dermal papilla stem cell exosomes. These aim to regenerate hair rather than just slow hair loss.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community GT20029 and PP405 the new fin and min that we been waiting for ?

36 upvotes 1 year ago

PP405 and GT20029 are new hair loss treatments with different mechanisms from traditional options like Minoxidil and Finasteride. PP405 targets hair follicle stem cells to reactivate growth, while GT20029 works as an androgen receptor deleter, both requiring ongoing use for effectiveness.

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 39 upvotes 3 years ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

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Learn

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learn Stem Cell Factor

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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