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Did you mean Cytokeratins?

Glossary Cytokeratins

fibrous proteins providing structural support in epithelial cells

Cytokeratins, also known as keratin proteins or CKs, are a group of fibrous structural proteins that form the intermediate filaments in epithelial cells. They provide mechanical support and help maintain the integrity of cells and tissues. In a clinical context, cytokeratins are often used as biomarkers in the diagnosis and study of various cancers, as their expression patterns can indicate the type and origin of a tumor.

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research Cytokeratin 15 expression in trichoepitheliomas and a subset of basal cell carcinomas suggests they originate from hair follicle stem cells

133 citations , March 1999 in “Journal of Cutaneous Pathology”

This study found that keratin 15 expression in trichoepitheliomas and some basal cell carcinomas suggests a link to hair follicle stem cells in the bulge.

research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia

54 citations , January 2009 in “British Journal of Dermatology”

This study found that in scarring alopecia, stem cells are differentially localized, suggesting that both inner and outer root sheath stem cells, rather than just follicular bulge stem cells, are involved.

research Cytokeratin 15 expression in central, centrifugal, cicatricial alopecia: new observations in normal and diseased hair follicles

14 citations , January 2011 in “Journal of Cutaneous Pathology”

This study found that CK15 is an unreliable marker for assessing bulge zone integrity in cicatricial alopecia follicles due to its altered expression in diseased conditions.

research Immunohistochemical expression of cytokeratin 15, cytokeratin 19, follistatin, and Bmi-1 in basal cell carcinoma

10 citations , December 2015 in “International Journal of Dermatology”

This study suggests that basal cell carcinoma and trichoblastoma may share differentiation toward the hair follicle, as indicated by strong positivity in CK 15, follistatin, and Bmi‐1 markers.