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research Controlled Evaluation Study of Serum Level of Zinc and Iron in Patients with Androgenetic Alopecia (REVISED)

February 2023 in “El-Minia Medical Bulletin”

This study found that female patients with androgenetic alopecia had significantly lower serum zinc and iron levels compared to healthy controls, suggesting supplementation may be beneficial.

research A placebo-controlled, double-blind crossover study of fluoxetine in trichotillomania

180 citations , November 1991 in “American Journal of Psychiatry”

This study found that fluoxetine did not demonstrate short-term efficacy in treating trichotillomania in a placebo-controlled, double-blind crossover setting.

research Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: A randomized, double-blind, placebo-controlled, phase III study

92 citations , June 2010 in “Journal of The American Academy of Dermatology”

This study found that 0.5 mg of dutasteride significantly improved hair growth compared to placebo and was well tolerated over six months in men with male pattern hair loss.

research A double-blind, placebo-controlled study of inositol in trichotillomania

18 citations , November 2016 in “International clinical psychopharmacology”

This study found that in a 10-week trial, inositol did not significantly reduce trichotillomania symptoms compared to placebo, although 42.1% of inositol-treated patients felt 'much or very much improved' at the study's end.

research Minoxidil 2% lotion for eyebrow enhancement: A randomized, double-blind, placebo-controlled, spilt-face comparative study

13 citations , November 2013 in “The Journal of Dermatology”

This study suggests that minoxidil 2% lotion is a safe and effective treatment for enhancing eyebrows, showing better results than placebo after 16 weeks.

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Community Join

5 / 383 results

community Do studies say Finasteride shed is real?

in Finasteride/Dutasteride 12 upvotes 1 year ago

Finasteride may cause hair shedding as part of the regrowth process, but there are no controlled trials confirming this. The shedding idea is mostly based on anecdotal reports and comparisons to how minoxidil works.

community Heads Up on Future Study: "Influence of Creatine Monohydrate Supplementation on Androgens and Global Hair Assessments"

22 upvotes 6 years ago

Creatine supplementation may increase DHT levels, potentially affecting hair loss. A study is examining this effect, with participants taking 5 grams of creatine daily for six months.

community Brief summary of new dutasteride study linked to infertility and the limitations/problems with the study

in Finasteride/Dutasteride 34 upvotes 1 year ago

Dutasteride treatment may decrease sperm concentration, but levels remain above WHO recommendations and recover after discontinuation. The study has limitations, including small sample size and lack of pre-treatment sperm data, and does not assess other fertility factors.

community Clascoterone study going on right now

351 upvotes 2 years ago

A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

community Recent Study finds Laser caps are more effective than 5% minoxidil for AGA

in Research/Science 124 upvotes 2 years ago

Laser caps are found to be more effective than 5% minoxidil for treating hair loss, and when combined with minoxidil, they are even more effective. Some users report positive results with laser treatments, while others see no change; the devices are FDA approved, but opinions on their efficacy vary.

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Learn

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learn Follistatin

Are there any clinical studies supporting follistatin as a hair loss treatment? There is no controlled human trial showing follistatin treats hair loss; the published work is mouse and laboratory biology on the activin/follistatin signalling system, plus one small 2011 phase 1 injection study of a combination product, so follistatin remains experimental and unapproved.

learn Setipiprant

Is Setipiprant taken orally or applied topically, and what do studies show about its results? Every published human study of setipiprant used oral tablets; no peer-reviewed trial has tested a topical version. Results were inconsistent in seasonal allergic rhinitis, and the one controlled hair-loss trial (DuBois 2021, 169 men, 24 weeks) found no significant regrowth. It is an experimental, unapproved compound.

learn L-cysteine

Can topical products with L-cysteine repair damaged hair or prevent breakage? No controlled studies show that topical L-cysteine products repair damaged hair or prevent breakage; hair outside the scalp is not living tissue and cannot regenerate.

learn Pyrithione Zinc

How does pyrithione zinc help reduce dandruff and irritation related to hair loss? In small controlled studies, zinc pyrithione shampoo reduced dandruff; lab studies suggest it works by slowing the growth of Malassezia yeast. It has not been shown to treat hair loss.

learn Melatonin

Hormone that regulates sleep, sold as a supplement

Is melatonin better as a supplement or applied to the scalp? No study has compared oral and topical melatonin head to head. Topical melatonin has one small placebo-controlled pilot trial in 40 women plus a set of mostly uncontrolled studies of a cosmetic solution; oral melatonin has no published hair-loss trial at all.

learn Ketoconazole

Antifungal, best known as a dandruff shampoo

learn Stemoxydine

Cosmetic ingredient made by L'Oréal

learn Lavender

Plant essential oil used in scalp products

learn HMI-115

Experimental antibody that blocks the prolactin receptor

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