August 2023 in “Scientia Pharmaceutica” In this study, researchers evaluated the stability and color changes of compounded minoxidil formulations used for alopecia, finding that while the formulations remained chemically and microbiologically stable for up to 380 days, significant color changes were observed, which likely do not affect the product's effectiveness.
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January 2023 in “Journal of Clinical Medicine” This paper presents the first reported case of Acute Localized Exanthematous Pustulosis linked to topical minoxidil use, suggesting a contact-induced hypersensitivity reaction as a potential mechanism.
January 2025 in “Journal of Pharmacognosy and Phytochemistry” This study developed plant-pigment-based shampoos using extracts from Neem, Fenugreek, Hibiscus, and Butterfly Pea, which demonstrated stability, antimicrobial properties, and potential scalp benefits such as hair growth promotion and dandruff reduction, making them a promising alternative to synthetic dyes.
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June 2021 in “International journal of pharmaceutical compounding” This study found that compounded minoxidil solutions in a propylene glycol-free and alcohol-reduced foam remained stable for 180 days, meeting United States Pharmacopeia standards for strength, pH, and antimicrobial effectiveness.
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June 2013 in “PubMed” This study found that minoxidil in Espumil Foam Base remains stable for at least 90 days when stored at room temperature and protected from light.