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GlossaryCD68 (Cluster of Differentiation 68)

protein marker on macrophages and monocytes in immune response

CD68 is a protein found on the surface of certain immune cells, such as macrophages and monocytes. It is often used as a marker in medical research and pathology to identify and study these cells, particularly in the context of inflammation and tissue repair.

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research Conditioned Media Derived from Mesenchymal Stem Cell Cultures: The Next Generation for Regenerative Medicine

88 citations, January 2019 in “Journal of Tissue Engineering and Regenerative Medicine”

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

research Timing of Expression of the Core Clock Gene Bmal1 Influences Its Effects on Aging and Survival

237 citations, February 2016 in “Science Translational Medicine”

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

research Distinct Tooth Regeneration Systems Deploy a Conserved Battery of Genes

September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Different fish use the same genes to regrow teeth.

research Pitx2, A β-Catenin-Regulated Transcription Factor, Regulates The Differentiation Of Outer Root Sheath Cells Cultured In Vitro

51 citations, February 2009 in “Journal of dermatological science”

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

research 2,3,7,8-Tetrachlorodibenzo-p-dioxin Increases the Expression of Genes in the Human Epidermal Differentiation Complex and Accelerates Epidermal Barrier Formation

86 citations, August 2011 in “Toxicological sciences”

TCDD speeds up skin barrier formation by increasing certain gene expressions.

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community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community March 21st vs July 9th! Topical fin, minox, latanoprost, and biotin

in Progress Pictures 118 upvotes 1 year ago

The user "cooler1082" shared their progress pictures for hair loss after using topical finasteride, minoxidil, latanoprost, and biotin. Other users commented on the positive results and asked about the specific dosages used. One user mentioned that latanoprost is an eye medication that has shown some potential for treating hair loss.

community Progressive insomnia (treatment-resistant) due to Finasteride

in Finasteride/Dutasteride 9 upvotes 2 years ago

A medical student experienced hair loss slowing with Finasteride but developed severe, treatment-resistant insomnia. They tried various medications with little effect, suspecting Post-Finasteride Syndrome, and others suggested the insomnia might be linked to Finasteride's impact on neurosteroids.

community An argument for why we should take topical Dutasteride seriously

in Research/Science 85 upvotes 3 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.

community Should I dedicate my university studies to solving hair loss?

in Research/Science 373 upvotes 1 year ago

A 20 year old male who is balding and considering switching to a biology/chemistry program in order to find a low-cost, accessible solution for hair loss. Replies discuss the merits of this idea as well as potential treatments such as Minoxidil, finasteride, RU58841, TM5614, and ADQ.

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