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GlossaryCD73

enzyme converting extracellular AMP to adenosine, impacting inflammation

CD73, also known as ecto-5'-nucleotidase, is an enzyme found on the surface of many cell types. It plays a crucial role in the immune system by converting extracellular AMP (adenosine monophosphate) into adenosine, which has anti-inflammatory effects. This enzyme is significant in various physiological processes, including tissue protection and repair, and is being studied for its potential role in cancer and autoimmune diseases.

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research The Adenosine-Generating Ecto-Enzyme CD73 Regulates Human Hair Growth

August 2016 in “Journal of Investigative Dermatology”

The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.

research Tregs: Where We Are and What Comes Next?

130 citations, November 2017 in “Frontiers in Immunology”

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

1 citations, August 2016 in “Journal of Investigative Dermatology”

Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.

research Human Hair Follicles Can Smell: OR2AT4-Mediated Hair Growth Regulation

August 2016 in “Journal of Investigative Dermatology”

Human hair follicles have a scent receptor that can influence hair growth.

research Exploring the Role of UC-MSC-Derived Exosomes in Boosting HHDPCs Proliferation for Hair Growth via AKT Activation

January 2024

UC-MSC-derived exosomes may help treat hair loss by promoting hair cell growth through AKT activation.

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