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      learn Dexpanthenol

      precursor of vitamin B5 with hair stimulating effects

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      natural substance from Neem tree with medicinal and pesticidal properties

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

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      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  207 upvotes 5 days ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community What blood markers to get tested before starting any 5-AR inhibitor?

      in Treatment  4 upvotes 1 year ago
      The conversation is about which blood markers to test before starting a 5-AR inhibitor for hair loss. The user mentions already testing Total T, Free T, SHBG, Estradiol, Haematocrit, Red blood cell count, and White cell count, and asks if DHT or additional markers are needed.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  415 upvotes 2 months ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Fresh off the press: Dutasteride may cause chronic infertility

      in Research/Science  639 upvotes 2 months ago
      Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.