Search

for
Search:

Research

5 / 1000+ results

research Identification of microRNAs involved in growth arrest and cell death in hydrogen peroxide-treated human dermal papilla cells

12 citations , April 2014 in “Molecular Medicine Reports”

In this study, transcriptome analysis identified 68 differentially expressed miRNAs in human dermal papilla cells treated with hydrogen peroxide, suggesting they play a significant role in growth arrest and apoptosis.

research Intensive stress impedes hair follicle growth through triggering cell cycle arrest of hair follicle stem cells

March 2025 in “The FASEB Journal”

In this study on mice, intensive stress through methods like resiniferatoxin injections and physical restraint was found to inhibit hair follicle growth, with the mechanism involving the sympathetic nervous system and the cAMP signaling pathway in hair follicle stem cells.

research Cedrol restricts the growth of colorectal cancer in vitro and in vivo by inducing cell cycle arrest and caspase-dependent apoptotic cell death

January 2022 in “International Journal of Medical Sciences”

This study investigated the effects of cedrol on colorectal cancer and found that it inhibited cell proliferation and induced cell cycle arrest and apoptosis in cell models, while in vivo, it suppressed cancer progression and improved survival at a well-tolerated dose.

research Author response: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes

September 2020

This study observed that nevus melanocytes do not exhibit signs of senescence, suggesting that their growth arrest is due to cell interactions and not directly caused by BRAF activation.

research XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity

4 citations , September 2020 in “Cell division”

In this study, XMU-MP-1 unexpectedly reduced cell proliferation and altered cell cycle progression in a model human hair follicle, possibly due to off-target kinase inhibition.

View more "cell growth arrest" in research →

Community Join

5 / 553 results

community I Guess balding is cured so should we close subreddit and move to hairstyling photos 😁 Botox-like nerve blocking reveals potential way to fully regenerate skin without scarring

6 months ago

Baldness is difficult to cure because current treatments like finasteride, dutasteride, and minoxidil only prevent hair shedding, and new developments are mostly ineffective. Botox shows potential in aiding skin regeneration and hair growth, but maintenance therapy with treatments like dutasteride and minoxidil may still be necessary.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community P-1075: a BETTER version of Minoxidil

11 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community TDM-105795 phase 2 results are in!

27 upvotes 2 years ago

TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

community Am I missing something with pp405?

34 upvotes 1 year ago

PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

View more "cell growth arrest" in community →

Learn

6 / 800 results

learn Stem Cell Factor

What is stem cell factor and why is it used in hair growth treatments? Stem cell factor is a signalling protein linked to hair colour in lab and mouse studies; it is not a proven hair-loss treatment in people.

learn Hair Transplant

Can PRP be combined with a hair transplant? Providers routinely offer PRP alongside a hair transplant and most say it speeds healing and supports graft survival; the published human studies are small and mixed, so the size of any benefit is unsettled.
Is a hair transplant permanent? Transplanted hair usually lasts long term, but it is not guaranteed and the hair around it can keep thinning, so the overall result can change with time.

learn Procyanidin

What is Procyanidin, and how does it encourage hair growth at the follicle level? In mouse cell and animal studies, procyanidin B-2 increased hair-cell growth. Small human trials, all run by the company that developed the ingredient, reported modest gains; it is not a proven or approved hair-loss treatment.

learn Thymosin Beta 4

What should users understand about the scientific status of Thymosin Beta 4 in hair growth therapies? Thymosin Beta 4 is not an approved treatment for hair loss, and its hair evidence comes only from animal and cell studies. Its grey-market form, TB-500, is flagged by the FDA for safety risks and banned in sport.

learn Exosomes

Tiny cell-derived particles offered by clinics as an injectable treatment

learn Follistatin

Protein that blocks activin, a growth-regulating signal

View more "cell growth arrest" in learn →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →