Search

for
Search:

Did you mean Cell Fate Decisions?

Glossary Cell Fate Decisions

process by which cells determine their future identity and function

Cell fate decisions refer to the process by which cells determine their future identity and function during development. This involves a series of signals and regulatory mechanisms that guide a cell to become a specific type, such as a skin cell, nerve cell, or hair follicle cell. Understanding these decisions is crucial for fields like regenerative medicine and treating conditions like alopecia, where promoting the correct cell fate can help regenerate hair follicles.

Related Terms

Research

5 / 1000+ results

research Par3–mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN

July 2021

This study found that the proteins Par3, mInsc, and Gαi3 cooperate to regulate LGN polarization and promote perpendicular cell divisions during murine epidermal morphogenesis.

research Cell fate decisions: emerging roles for metabolic signals and cell morphology

100 citations , November 2017 in “EMBO Reports”

This review discusses the roles of metabolism, reactive oxygen species, intracellular pH, and cell morphology in influencing cell fate decisions during stem cell differentiation but reports no new experimental results.

research Decision letter: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes

August 2020

This study suggests that the growth arrest of nevus melanocytes is not due to oncogene-induced senescence but rather to collective cell interactions, similar to those in normal tissue size regulation.

research Decision letter: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation

April 2018

This study found that fibroblast growth factor 20 (Fgf20) orchestrates the movement and behavior of dermal fibroblasts, directing their formation into dermal condensates during hair follicle development in mice.

research Decision letter: Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo

November 2022

This study found that in live mouse epidermal stem cells, chromatin compaction is heterogenous and reflects differentiation status, with transcriptional changes largely preceding chromatin rearrangements during differentiation.

View more "cell decisions" in research →

Community Join

5 / 784 results

community What do you guys think of stem cell hai restoration?

10 upvotes 8 months ago

Stem cell hair restoration lacks scientific evidence and is often considered a scam. Effective hair loss treatments include hair transplants, Minoxidil, and Finasteride, but stem cell treatments are not proven.

community Good news for stem cells hair therapies - US federal judge: using patients' stem cells does NOT fall under FDA jurisdiction

26 upvotes 4 years ago

A US federal judge ruled that using patients' stem cells for medical treatments is not under FDA jurisdiction, potentially speeding up development of stem cell-based hair loss therapies. Some users are optimistic about increased research and development, while others express skepticism about the ruling's impact on safety and efficacy standards.

community Quote from Pelage (PP-405) Spokesperson...

122 upvotes 10 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community Estenove Transplant Review From NYC Guy Mid 20s

1 upvotes 1 year ago

The user had a hair transplant with Estenove, rating the overall experience 6/10 due to logistical issues, unmet expectations, and dissatisfaction with the results. They advise against pricier packages and express regret over the asymmetrical hairline, despite good customer service and post-op care.

community Curious on your thoughts on this article i stumbled upon.

5 upvotes 4 years ago

Concerns about dermarolling potentially causing collagen breakdown and cancer, with skepticism about the claims due to lack of scientific evidence. Users express doubts and discuss the validity of the article's claims.

View more "cell decisions" in community →

Learn

4 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Epidermal Growth Factor

learn Stem Cell Factor

What is stem cell factor and why is it used in hair growth treatments? Stem cell factor promotes hair growth by signaling cell survival and division.
How does stem cell factor help activate dormant hair follicles? Stem cell factor activates dormant hair follicles by signaling through the c-Kit receptor.
Are stem cell factor products safe for long-term scalp use? Stem cell factor products lack proven long-term safety for scalp use.
All 5 questions on Stem Cell Factor →

learn Apple stem cell

View more "cell decisions" in learn →

Clinics

6 / 64 results

All 64 clinic results →

Experts

— no results

Try a deeper search in experts →