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Expression Patterns of Glial Cell Line-Derived Neurotrophic Factor, Neurturin, Their Cognate Receptors GFRα-1, GFRα-2, and Common Signal Transduction Element c-Ret in Human Skin Hair Follicles

research Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles

18 citations , January 2008 in “Journal of The American Academy of Dermatology”

This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.

research RETRACTION: Causal Effects of Omega‐6 and LDL‐C on Androgenetic Alopecia: A Mendelian Randomization Study

June 2025 in “Skin Research and Technology”

The study's findings on omega-6 and hair loss are unreliable.

research Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway

October 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)”

This study found that finasteride induced infertility and increased endoplasmic reticulum stress in rats, but these effects were mitigated by DA-9401 administration.

research Topical retinoids: role and place in acne therapy

March 2024 in “Ukraïnsʹkij žurnal dermatologìï, venerologìï, kosmetologìï”

This source highlights that topical retinoids, particularly adapalene and its combinations, are crucial in treating acne due to their rapid action, sustained effects, and good tolerability; the study underscores the enhanced patient adherence with Deriva C MS gel for acne treatment.

research Incidence and risk factors for neonatal occipital alopecia: A retrospective study

February 2010 in “Journal of The American Academy of Dermatology”

This study found that among Chinese patients with alopecia areata, those with alopecia totalis or universalis had an earlier onset, longer disease duration, and more severe quality of life impact than those with patchy alopecia.

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Community Join

5 / 521 results

community Results dissappearing after 9 months, curious if anyone else has experienced the same.

1 upvotes 1 month ago

The user experienced initial hair growth with Him hair Chews (Finasteride, Minoxidil, Biotin, Vitamin C, Vitamin B5, Vitamin B6) but saw a return to the original state after 18 months. Suggestions included continuing medication, switching to dutasteride, and considering separate treatments or microneedling.

community Oral minoxidil vs Topical Minoxidil w/ Retinoic acid

6 upvotes 1 year ago

Topical minoxidil with retinoic acid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.

community 75 days on Oral Min & Oral Fin Retrograde Alopecia

64 upvotes 4 months ago

A user shared their 75-day progress using oral minoxidil, finasteride, ketoconazole shampoo, and dermastamping for retrograde alopecia, reporting significant improvement and increased body hair without side effects. They also discussed quitting smoking and the potential correlation between early beard growth and male pattern baldness.

community Stop the fear mongering of oral minoxidil its one of the best treatments available in 2020. It does not cause heart lesions or adverse cardiac effects like people claim. I am maintaining with just oral minoxidil with retrograde alopecia and diffuse thinning all over nw3 hairline

78 upvotes 5 years ago

Oral minoxidil is considered a safe and effective treatment for hair loss at low dosages, with minimal cardiac risks. Users report positive results, though some experience side effects like increased heart rate and skin changes, and consulting a doctor is advised.

community Recently went to a trichologist and got recommended these 4 products to treat AGA.

1 month ago

The trichologist recommended products with ingredients like retinol, caffeine, and placenta extract for AGA, but users believe these are ineffective and possibly a scam. They suggest consulting a dermatologist and using proven treatments like Minoxidil and Finasteride instead.

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Learn

6 / 801 results

learn Scalp Micropigmentation

Does scalp micropigmentation hurt? Scalp micropigmentation typically causes minimal discomfort, often described as light scratching.
How long does Scalp Micropigmentation last, and does it need touch-ups over time? Scalp micropigmentation lasts 2 to 8 years and requires touch-ups every 1 to 5 years.

learn Hair Transplant

Will transplanted hair fall out after a hair transplant? Transplanted hair is permanent but may temporarily shed before new growth occurs.

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn C 13-15 alkane

learn Vitamin C

Is your itchy scalp a sign that it’s missing vitamin C? Find out how it may help with patchy hair loss. An itchy scalp may indicate a vitamin C deficiency affecting hair health.
Why is Vitamin C important for hair and hair follicles? Vitamin C is essential for collagen synthesis and overall hair follicle health.

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Clinics

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Experts

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