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    Glossary Bulge Cells

    specialized stem cells in hair follicles aiding growth and repair

    Bulge cells are specialized stem cells located in the hair follicle's bulge area, which is a region near the base of the hair follicle. These cells play a crucial role in hair growth and regeneration, as they have the ability to differentiate into various cell types needed for the hair follicle's structure and function. For professionals, it's important to note that bulge cells are also involved in wound healing and can contribute to the regeneration of the epidermis.

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    1. Cytokeratin 15 expression in central, centrifugal, cicatricial alopecia: new observations in normal and diseased hair follicles Journal of Cutaneous Pathology · 2011 · 14 citations
    2. Morphometric Analysis of the Human Scalp Hair Follicle: Practical Implications for the Hair Transplant Surgeon and Hair Regeneration Studies Dermatologic Surgery · 2010 · 51 citations
    3. Faculty Opinions recommendation of Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2009
    4. Apoptosis coordinates with proliferation and differentiation during human hair follicle morphogenesis Journal of dermatological science · 2005 · 7 citations
    5. Immunopathogenesis of Primary Cicatricial Alopecia Research Portal (King's College London) · 2013
    6. Epidermal structure created by canine hair follicle keratinocytes enriched with bulge cells in a three‐dimensional skin equivalent model <i>in vitro</i>: implications for regenerative therapy of canine epidermis Veterinary dermatology · 2013 · 11 citations
    7. 1312 Nrf2 activation enhances the healing of cutaneous wounds through the activation of hair follicle stem cells Journal of Investigative Dermatology · 2018
    8. Stem cells and alopecia: a review of pathogenesis British Journal of Dermatology · 2012 · 33 citations
    9. Compartmentalized organization: a common and required feature of stem cell niches? Development · 2010 · 63 citations
    10. Role of bulge epidermal stem cells and TSLP signaling in psoriasis EMBO molecular medicine · 2019 · 19 citations
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