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    Glossary Hair Follicle Bulge

    specific region housing stem cells for hair growth

    The hair follicle bulge is a specific region located in the outer root sheath of the hair follicle. It serves as a reservoir for stem cells that are crucial for hair growth and regeneration, as well as for repairing the skin after injury. This area is essential for the cyclical nature of hair growth and plays a significant role in conditions like alopecia.

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    1. 1393 Lower proximal cup cells but not bulge stem cells regenerate hair follicles after chemotherapy injury Journal of Investigative Dermatology · 2018 · 1 citations
    2. Generation of the Krt24-CreERT2 Mouse Line Targeting Outer Bulge Hair Follicle Cells International Journal of Molecular Sciences · 2025
    3. Canine hair‐follicle keratinocytes enriched with bulge cells have the highly proliferative characteristic of stem cells Veterinary Dermatology · 2009 · 37 citations
    4. Bulge cells of human hair follicles: segregation, cultivation and properties Colloids and Surfaces B: Biointerfaces · 2006 · 27 citations
    5. The Hair Follicle Bulge: A Niche for Adult Stem Cells Microscopy and Microanalysis · 2011 · 19 citations
    6. Anagen hair follicle repair: Timely regenerative attempts from plastic extra‐bulge epithelial cells Experimental Dermatology · 2019 · 18 citations
    7. In vitro identification of a stem cell population from canine hair follicle bulge region 2017 · 5 citations
    8. Bulge-Derived Epithelial Cells Isolated from Human Hair Follicles Using Enzymatic Digestion or Explants Result in Comparable Tissue-Engineered Skin International Journal of Molecular Sciences · 2025 · 1 citations
    9. Characterization of Hair Follicle Bulge in Human Fetal Skin: The Human Fetal Bulge Is a Pool of Undifferentiated Keratinocytes Journal of Investigative Dermatology · 1995 · 96 citations
    10. Basal cell carcinoma possibly originates from the outer root sheath and/or the bulge region of the vellus hair follicle Archives of Dermatological Research · 1999 · 107 citations
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    Community 3

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