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Did you mean Hair Follicle Bulge?

GlossaryHair Follicle Bulge

specific region housing stem cells for hair growth

The hair follicle bulge is a specific region located in the outer root sheath of the hair follicle. It serves as a reservoir for stem cells that are crucial for hair growth and regeneration, as well as for repairing the skin after injury. This area is essential for the cyclical nature of hair growth and plays a significant role in conditions like alopecia.

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research Bulge Cells of Human Hair Follicles: Segregation, Cultivation, and Properties

27 citations, January 2006 in “Colloids and Surfaces B: Biointerfaces”

Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.

Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata

research Involvement of the Bulge Region with Decreased Expression of Hair Follicle Stem Cell Markers in Senile Female Cases of Alopecia Areata

20 citations, December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.

research In Vitro Identification of a Stem Cell Population from Canine Hair Follicle Bulge Region

5 citations, December 2017 in “Tissue and cell/Tissue & cell”

Researchers found stem cells in dog hair follicles using specific markers.

research Vibrissa Hair Bulge Houses Two Populations of Skin Epithelial Stem Cells Distinct by Their Keratin Profile

45 citations, December 2007 in “The FASEB journal”

There are two types of stem cells in rodent hair follicles, each with different keratin proteins.

research The Effects of Gamma Rays on the Regeneration of Hair Follicles Are Carried Over to Later Hair Cycles

5 citations, November 2015 in “International Journal of Radiation Biology”

Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.

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community M32, almost 3 moths, fin oral 1,25g/daily + min 2xday + keto 2% shapoo 1/week microneedling once a week

in Progress Pictures 31 upvotes 11 months ago

A 32-year-old man has been treating his hair loss with daily oral finasteride (1.25g), twice-daily topical minoxidil, weekly ketoconazole 2% shampoo, and weekly microneedling for almost three months, with no side effects from finasteride. He started with a Hamilton Norwood scale rating of 5 and has seen improvement without experiencing pain by using a 0.8mm needle length for microneedling.

community Redensyl Megathread !!!!

44 upvotes 4 years ago

Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community HairClone developing cell replacement treatments for Hair Loss

6 upvotes 5 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community Best Microneedle Lengths To Stimulate Stem Cells

in Microneedling 18 upvotes 1 year ago

Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

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