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research Oligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption

282 citations , April 2007 in “Journal of Agricultural and Food Chemistry”

This study found that apple polyphenol extract, particularly oligomeric procyanidins, inhibited pancreatic lipase activity and reduced triglyceride absorption in both mice and humans.

research Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study

37 citations , January 2002 in “British journal of dermatology/British journal of dermatology, Supplement”

This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.

research Biorevitalizing effect of a novel facial serum containing apple stem cell extract, pro‐collagen lipopeptide, creatine, and urea on skin aging signs

36 citations , October 2015 in “Journal of Cosmetic Dermatology”

In this study, a new apple stem cell extract serum significantly improved signs of skin aging and enhanced cell metabolism in human senescent fibroblasts, showing visible effects after one week of use.

research Investigation of topical application of procyanidin B-2 from apple to identify its potential use as a hair growing agent

32 citations , December 2000 in “Phytomedicine”

In this study, 1% procyanidin B-2 tonic significantly increased the number of total and terminal hairs on the scalp of male participants compared to a placebo after 6 months of use.

research Investigation of the topical application of procyanidin oligomers from apples to identify their potential use as a hair‐growing agent

28 citations , December 2005 in “Journal of cosmetic dermatology”

This study found that 0.7% apple procyanidin oligomers applied externally for six months significantly increased hair growth in men with male pattern baldness compared to placebo, with no observed adverse effects.

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Community Join

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community Does Apple cider vinegar interfere with oral minoxidil or finasteride?

3 upvotes 1 year ago

Apple cider vinegar, when taken as 1 tablespoon diluted with water daily, does not interfere with the absorption of oral minoxidil or finasteride.

community Applying topical Minoxidil 5% with a fine mist device vs drops?

7 upvotes 3 weeks ago

A user discusses using a fine mist device to apply 5% topical minoxidil for more even coverage on thinning hair compared to using drops. They are also taking oral finasteride and minoxidil, and are exploring if the mist method is as effective long-term.

community how do u guys apply minxoidil if you have long hair.

in Minoxidil 30 upvotes 2 months ago

Applying minoxidil with long hair can be challenging due to its oily appearance, but users suggest methods like using a topical applicator, parting hair, or applying to damp hair. Some prefer oral minoxidil for ease, while others use foam or adjust application techniques to target the scalp effectively.

community How do you guys apply liquid topicals to your whole scalp w hair?

14 upvotes 3 months ago

Applying liquid hair loss treatments like Minoxidil and RU58841 to the scalp without wasting product in the hair. Users suggest using droppers, syringes, or scalp massagers to ensure the liquid reaches the scalp effectively.

community Minoxidil night time application

2 upvotes 7 months ago

Apply minoxidil at least 1-2 hours before bed to ensure it dries and doesn't transfer to the pillow. Foam dries faster than liquid, and using a satin beanie after drying can help prevent transfer.

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Learn

10 / 800 results

learn Hair Fibers

How do you apply hair fibers correctly so they stay in place all day? Apply hair fibers to clean, dry hair and use a setting spray for better hold.

learn PP405

Can applying a mask with PP405 directly to thinning areas give your scalp the push it needs? No PP405 mask exists to test: PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier, it is not an anti-DHT ingredient, and it is not on sale. Its registered Phase 2 trial (NCT06393452) measured safety, not regrowth, and a rinse-out mask is in any case the wrong format for reaching the follicle.

learn Estradiol

Is applying Estradiol directly to the scalp effective for hormone-related hair thinning? There are no good-quality trials showing that estradiol applied to the scalp treats hormone-related thinning. Skin-applied estradiol can still enter the bloodstream and pass to others through contact.

learn Stemoxydine

How has stemoxydine been applied in studies, and what results were seen? Studies applied 5% stemoxydine to the scalp daily or 5 days a week for 3 months. No study has compared frequencies. Follow the product label and expect at most a modest change.

learn Minoxidil

Minoxidil: the application and its effects counted in months Some people notice a temporary increase in shedding when they start; the US over-the-counter label says results may take 2 to 4 months, and trials measured results at around 4 months to a year.

learn Procyanidin

Plant polyphenol found in apples and grape seeds

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Clinics

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Experts

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SMP Specialist
Kim Apple
Palm Beach Gardens, FL, United States