July 2026 in “Cell Transplantation” This study systematically reviewed 43 articles on the role of fibroblasts, especially dermal papilla cells, in androgenic alopecia, identifying androgen signaling and related pathways as key drivers of hair follicle miniaturization, which supports targeting dermal papilla cell dysfunction as a therapeutic strategy.
In this study, collagen type I, skin fibroblasts, and macrophages did not show remarkable changes in androgenic alopecia patients' scalp tissues after treatment with 1550 nm fractional Er:Glass laser, despite improved hair regrowth.
January 2026 in “Open MIND” This upcoming review will investigate the role of hair follicle fibroblasts in androgenetic alopecia, focusing on their interactions with androgens and impact on cellular signaling and fibrosis.
January 2026 in “Dermatologic Therapy” This study found that treatment with human foreskin fibroblast conditioned medium improved both objective measures like hair density and subjective satisfaction in patients with androgenetic alopecia.
December 2022 in “Plastic and Reconstructive Surgery” In this study, PRPF treatment was more effective than PRP alone in improving hair count and hair quality in androgenetic alopecia patients, with PRPF showing significant improvements in various hair growth parameters and having no statistical differences observed in the placebo group.