Expression of Collagen Type I, Skin Fibroblasts, and Macrophages After 1550 nm Erbium Glass Fractional Laser in Androgenic Alopecia

The study conducted by Heng Kunthearithy in 2019 aimed to determine the effects of a 1550 nm fractional Er:Glass laser on collagen type I, skin fibroblasts, and macrophages in patients with androgenic alopecia. The study involved five subjects, from whom fifteen specimens were collected and analyzed before and after laser treatment. The specimens were stained to evaluate collagen type I, skin fibroblasts, and macrophages. However, the study found no significant changes in these parameters after treatment with the erbium glass fractional laser, despite improved hair regrowth in the patients. The study concluded that further research is needed to determine the optimal laser parameters and to evaluate the effects of the laser on inflammatory cells or other cytokines in patients with androgenic alopecia.