learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 17 resultslearn Pyrilutamide
highly targeted anti-androgen that might have minimal systemic effects
learn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
learn Ketoconazole
antifungal with some anti-androgenic benefits, often used as a shampoo
learn Minoxidil
An essential vasodilator with some anti-androgenic effects, has excellent safety record
Research
5 / 1000+ resultsresearch The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath
Hair follicle stem cells are promising for blood vessel formation and tissue repair.
research Asymmetric Adhesive SIS-Based Wound Dressings for Therapeutically Targeting Wound Repair
The new wound dressing improves healing and tissue repair better than conventional dressings.
research 3D Co-Culture Model of Endothelial Colony-Forming Cells Reverses Late Passage Adipose-Derived Stem Cell Senescence for Wound Healing
A 3D cell model can rejuvenate stem cells to improve wound healing.
research MiR-150 Regulates Endothelial Progenitor Cell Differentiation via Akt and Promotes Thrombus Resolution
miR-150 helps blood vessel cells develop and speeds up blood clot healing.
research Fibrous Scaffolds Potentiate the Paracrine Function of Mesenchymal Stem Cells: A New Dimension in Cell-Material Interaction
Special fiber materials boost the healing properties of certain stem cells.
Community Join
5 / 1000+ resultscommunity Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.
A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.
community Does melatonin dissolve in isopropyl alcohol
The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Dutasteride absolutely nukes hair DHT
Dutasteride significantly reduces DHT levels, potentially more effectively than finasteride, and is used to treat hair loss. Some users report side effects like reduced libido and mood changes, while others experience hair regrowth and increased testosterone.
community Switch from fin to dut and its worse
Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.