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research The mouse hairy ears mutation exhibits an extended growth (anagen) phase in hair follicles and altered Hoxc gene expression in the ears

10 citations , November 2008 in “Veterinary Dermatology”

In this study, the misshaped and hairy ear phenotype in mutant mice was linked to mis-expression of certain Hoxc genes due to a chromosomal inversion.

research Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression

69 citations , May 1997 in “Veterinary Pathology”

This study found that the angora mouse mutation prolongs the anagen phase, resulting in excessively long hair and follicular abnormalities, without involving circulating hair cycle factors.

research Skin, hair and beyond: the impact of menopause

14 citations , April 2022 in “Climacteric”

This review discusses the impact of HRT on menopausal skin and hair symptoms and argues that potential benefits should be part of informed decision-making for managing menopause.

research Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment

17 citations , September 2020 in “Inflammation and Regeneration”

In this study, researchers found that WNT activation influenced FGF expression in human scalp-derived fibroblasts, with mouse model results showing FGF9 increased hair follicle number and diameter, while FGF7 reduced diameter.

research Local Injection of Hepatocyte Growth Factor/Scatter Factor (HGF/SF) Alters Cyclic Growth of Murine Hair Follicles

109 citations , April 1998 in “Journal of Investigative Dermatology”

This study found that recombinant human HGF/SF injections altered hair follicle growth cycles and mildly promoted hair elongation in mice, depending on their hair cycle stage.

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Community Join

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community Baldness Breakthrough: microRNA Stimulates Hair Growth in Aging Follicles

316 upvotes 3 years ago

miR-205, a tiny RNA, can stimulate hair growth by softening aging hair follicle stem cells in mice. Future tests aim to see if this can work in humans.

community The Real Reason For Hair Loss?

8 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.

community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT

14 upvotes 3 years ago

SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.

community Results of enclomiphene with finasteride?

in Finasteride/Dutasteride 5 upvotes 4 weeks ago

The user experienced significant hair growth using oral minoxidil and finasteride but started shedding after adding enclomiphene to improve athletic performance. They are seeking advice on managing the shedding while continuing the treatment.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

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Learn

10 / 801 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Hair Transplant

Who is a good candidate for a hair transplant? Good candidates for hair transplants have sufficient donor hair and stable hair loss patterns.

learn Scalp Micropigmentation

Can scalp micropigmentation be removed? Scalp micropigmentation can be removed using laser treatments, but results may vary.

learn Folic acid

How does folic acid support hair follicle health and growth at a cellular level? Folate is required for the DNA synthesis that fast-dividing hair matrix cells depend on, and severe deficiency causes anemia—but no published trial has given folic acid to people with hair loss and measured the result, so a growth effect is a mechanism, not a finding.

learn Estradiol

an estrogen promoting hair regrowth more commonly used in women

learn Caffeine

Does caffeine stimulate hair growth or only slow hair loss? Caffeine stimulates hair follicles in laboratory cultures, and one open-label trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint; there is no placebo-controlled evidence that it regrows hair, and none at all in alopecia areata or telogen effluvium.

learn Procyanidin

Are Procyanidin based hair tonics or shampoos effective against androgenic alopecia? Procyanidin-based hair tonics may promote hair growth but lack definitive evidence for AGA.

learn Platelet-Rich Plasma

growth factors taken from your blood and injected into your scalp to stimulate hair

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Bimatoprost

a synthetic prostamide used to treat eyelashes also shows promise for stimulating hair growth on scalp

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Clinics

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