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learn Dexpanthenol

Provitamin B5, a moisturiser in hair and skin products

What does dexpanthenol do for hair and scalp health? Dexpanthenol (provitamin B5) is used in hair and scalp products as a moisturiser. No controlled trial has shown that it treats hair loss on its own.
Does dexpanthenol promote hair growth? Reviews describe dexpanthenol mainly as a moisturiser for skin. No controlled trial has shown that it promotes hair growth.
Should dexpanthenol be rinsed out or left in? No study has compared leave-in and rinse-off dexpanthenol. Leave-in products give longer contact; rinse-off may suit fine or oily hair.
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Research

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research Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells

13 citations , September 2021 in “Current Issues in Molecular Biology”

This study suggests that D-panthenol may promote hair growth by enhancing cell viability, suppressing apoptosis markers, and elongating the anagen phase in human hair follicle cells.

research Dexpanthenol ameliorates lipopolysaccharide-induced cardiovascular toxicity by regulating the IL-6/HIF1α/VEGF pathway

10 citations , January 2024 in “Heliyon”

This study found that dexpanthenol treatment reduced inflammation, oxidative stress, and apoptosis in rats, providing a protective effect against lipopolysaccharide-induced cardiac and endothelial damage.

research Dexpanthenol may be a novel treatment for male androgenetic alopecia: Analysis of nine cases

7 citations , April 2020 in “Dermatologic Therapy”

In this study, nine male cases of androgenetic alopecia showed marked improvement after receiving systemic dexpanthenol treatment.

research Systemic dexpanthenol as a novel treatment for female pattern hair loss

5 citations , September 2020 in “Journal of Cosmetic Dermatology”

This study reported that weekly intramuscular dexpanthenol may improve quality of life and satisfaction with hair appearance in women with female pattern hair loss, with no side effects observed.

research Sulforaphane, L-Menthol, and Dexpanthenol as a Novel Active Cosmetic Ingredient Composition for Relieving Hair Loss Symptoms

3 citations , June 2021 in “Cosmetics”

This study found that sulforaphane may help alleviate hair loss by increasing hair count after 18 weeks of use and enhancing the expression of a DHT-degrading enzyme in cellular models.

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