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Glossary 7,12-Dimethylbenz[a]anthracene

potent chemical carcinogen used in cancer research

7,12-Dimethylbenz[a]anthracene (DMBA) is a potent chemical carcinogen commonly used in research to induce cancer in laboratory animals for the study of cancer mechanisms and potential treatments. It is a polycyclic aromatic hydrocarbon that can cause mutations in DNA, leading to the development of tumors.

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research Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.

33 citations , March 1994 in “PubMed”

This study reported that high ornithine decarboxylase expression and decreased keratin K1 and K10 expression may serve as useful markers for early stages of tumor development in mouse skin.

research The Vitamin D Receptor as Tumor Suppressor in Skin

55 citations , January 2020 in “Advances in experimental medicine and biology”

This study suggests that vitamin D and its receptor may protect against the development of epidermal tumors following UV radiation by regulating specific cellular signaling pathways.

research Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice

100 citations , August 2011 in “Journal of Investigative Dermatology”

Lack of vitamin D receptor increases skin tumor risk by boosting hedgehog signaling.

research Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis

148 citations , May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that mice lacking the vitamin D receptor (VDR) developed skin tumors more rapidly than those with normal VDR activity, regardless of 1,25-dihydroxyvitamin D(3) presence.

research Ligand‐Independent Actions of the Vitamin D Receptor: More Questions Than Answers

11 citations , November 2021 in “JBMR plus”

This review discusses the role of the unliganded vitamin D receptor in hair follicle cycling and tumor formation in mice and reports no new experimental findings.

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community 7,1/2 months of Minoxidil, 2 months finasteride. 20M

in Progress Pictures 221 upvotes 1 year ago

A 20-year-old shared progress on hair regrowth after 7.5 months of minoxidil and 2 months of finasteride, reporting no negative side effects and healthier hair. The user also improved their diet, stopped creatine, and experienced positive changes in hair and overall appearance.

community 7 Months Progress -- 1 Mg Finasteride, 5 mg Minoxidil, and Derma rolling

in Progress Pictures 260 upvotes 1 year ago

Significant hair regrowth was achieved using 1 mg Finasteride, 5% Minoxidil, and dermarolling, with a switch from a 0.5 mm to a 1 mm roller after two months. The user is happy with the results but is still considering a hair transplant for more density.

community 7 months progress of chewable finasteride 1.2 mg and minoxidil 3 mg

98 upvotes 1 month ago

The user shared seven months of progress using chewable finasteride 1.2 mg and minoxidil 3 mg, showing some improvement in hair thickness, particularly at the crown. Suggestions included continuing the medication for up to two years, considering a hair transplant, and maintaining consistency with the treatment.

community 7 months on topical 5% Min + 0.1% Fin (once daily) – How's my progress?

in Is this regrowth? 21 upvotes 2 months ago

The user has been using a topical treatment of 5% Minoxidil and 0.1% Finasteride once daily for over 7 months, along with ketoconazole shampoo, and reports reduced hair shedding and perceived hair thickening. Feedback from others is mixed, with some noticing improvement and others seeing no change or worsening.

community [30M] Regenera Activ (7 Weeks) + Topical Dutasteride/Minoxidil (12 Weeks)

in Progress Pictures 187 upvotes 1 year ago

A 30-year-old man shared his positive experience with hair regrowth using Regenera Activ, topical Dutasteride, Minoxidil, and PRP over 12 weeks. He plans to continue with injectable Dutasteride and emphasizes the importance of starting treatment early to combat hair loss.

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learn Hair Transplant

When can I return to work after a hair transplant? Most patients can return to work within 2 to 7 days after a hair transplant.
What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
How long does a hair transplant procedure take? A hair transplant procedure typically takes 4 to 8 hours.

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