Early-Age-Dependent Selective Decrease of Differentiation Potential of Hair-Follicle-Associated Pluripotent Stem Cells to Beating Cardiac-Muscle Cells

    July 2016 in “ Cell cycle/Cell cycle (Georgetown, Tex. Online) ”
    Aiko Yamazaki, Yuko Hamada, Nobuko Arakawa … Yasuyuki Amoh
    Studysummary This study observed that HAP stem cells from the whiskers of young mice near the ear differentiated into heart-muscle cells more efficiently than those from older mice or other whisker locations.
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    Research cited in this study 9

    1. Aging Hair Follicles Rejuvenated by Transplantation to a Young Subcutaneous Environment Cell cycle/Cell cycle (Georgetown, Tex. Online) · 2016
    2. Isoproterenol Directs Hair Follicle-Associated Pluripotent (HAP) Stem Cells to Differentiate In Vitro to Cardiac Muscle Cells Which Can Be Induced to Form Beating Heart-Muscle Tissue Sheets Cell cycle/Cell cycle (Georgetown, Tex. Online) · 2016
    3. Extensive Hair Shaft Growth After Mouse Whisker Follicle Isolation, Cryopreservation, and Transplantation in Nude Mice PloS one · 2015
    4. From Hair to Heart: Nestin-Expressing Hair-Follicle-Associated Pluripotent Stem Cells Differentiate to Beating Cardiac Muscle Cells Cell Cycle · 2015
    5. Human Hair Follicle Pluripotent Stem Cells Promote Regeneration of Peripheral Nerve Injury: An Advantageous Alternative to ES and iPS Cells Journal of Cellular Biochemistry · 2009
    6. Multipotent Hair Follicle Stem Cells Promote Repair of Spinal Cord Injury and Recovery of Walking Function Cell Cycle · 2008
    7. Implanted Hair Follicle Stem Cells Form Schwann Cells That Support Repair of Severed Peripheral Nerves Proceedings of the National Academy of Sciences · 2005
    8. Multipotent Nestin-Positive, Keratin-Negative Hair-Follicle Bulge Stem Cells Can Form Neurons Proceedings of the National Academy of Sciences · 2005
    9. Nestin Expression in Hair Follicle Sheath Progenitor Cells Proceedings of the National Academy of Sciences · 2003

    Related research 1

    1. Hair Follicle Stem Cell Marker Nestin Expression in Regenerating Hair Follicles of Patients with Alopecia Areata European Journal of Dermatology · 2011