Extracellular Vesicles in Regenerative and Cosmetic Medicine: Safety, Clinical Effectiveness, Therapeutic Applications, and Regulatory Challenges

    June 2026 in “ International Journal of Molecular Sciences ”
    Candelaria Contreras, Amin Ariza‐Donado
    Studysummary This review discusses the potential benefits and challenges of using extracellular vesicles in aesthetic medicine but reports no new clinical results, highlighting the need for rigorous validation and stronger regulatory oversight.
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    Research cited in this study 8

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    2. Adverse Reactions Following Intradermal Injection of Exosome-Based Formulations: A Case Series Journal of Cosmetic Dermatology · 2025
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    4. Adipose Mesenchymal Stem Cell-Derived Exosomes Versus Platelet-Rich Plasma Treatment for Photoaged Facial Skin: An Investigator-Blinded, Split-Face, Non-Inferiority Trial Journal of Cosmetic Dermatology · 2025
    5. Exosomes for Aesthetic Dermatology: A Comprehensive Literature Review and Update Journal of Cosmetic Dermatology · 2025
    6. Exosomes in Cosmetic Dermatology: A Review of Benefits and Challenges Journal of Drugs in Dermatology · 2024
    7. Exploring the Reality of Exosomes in Dermatology Anais Brasileiros de Dermatologia · 2024
    8. Exosomes for Treating Hair Loss: A Review of Clinical Studies Dermatologic Surgery · 2024