Adrenal and Gonadal Activity, Androgen Concentrations, and Adult Height Outcomes in Boys With Silver-Russell Syndrome

    December 2019 in “ Frontiers in endocrinology ”
    Kjersti Kvernebo Sunnergren, Carina Ankarberg‐Lindgren, Jovanna Dahlgren
    Studysummary This study found that high prepubertal and pubertal androgen levels, originating from both adrenal and gonadal secretion, were negatively associated with adult height outcomes in males with Silver-Russell syndrome.
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    Research cited in this study 3

    1. Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth International journal of reproductive medicine · 2014
    2. Biosynthesis of Dihydrotestosterone by a Pathway That Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line Journal of Investigative Dermatology · 2009
    3. Decreased Androgen Receptor Gene Methylation in Premature Pubarche: A Novel Pathogenetic Mechanism? ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2006