The Nuclear Vitamin D Receptor: Biological and Molecular Regulatory Properties Revealed
March 1998
in “
Journal of bone and mineral research
”
vitamin D receptor VDR gene expression regulation calcium homeostasis phosphate homeostasis bone mineralization immune system neural system hair development skin development VDR knockout mice hereditary hypocalcemic vitamin D–resistant rickets HVDRR alopecia bone mineralization defects vitamin D metabolism VDR mutations vitamin D endocrine system therapeutic target vitamin D receptor VDR hair loss skin health alopecia bone health vitamin D system
Studysummary This review discusses the molecular role of the vitamin D receptor in regulating various biological actions such as bone mineralization and reports no new clinical results, highlighting the complexity of vitamin D's function in multiple tissues.
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