Effect of Petroleum Ether and Ethanol Fractions of Seeds of Abrus Precatorius on Androgenic Alopecia

    December 2011 in “ Revista Brasileira de Farmacognosia ”
    Sukirti Upadhyay, Vinod Kumar Dixit, Ashoke Kumar Ghosh, Vijayender Singh
    Studysummary In this animal study, petroleum ether and ethanolic extracts of Abrus precatorius seeds appeared to reverse androgen-induced alopecia in male albino rats by inhibiting the 5α-reductase enzyme, similar to finasteride.
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    Research cited in this study 9

    1. Effect of Cuscuta Reflexa Roxb on Androgen-Induced Alopecia Journal of Cosmetic Dermatology · 2008
    2. Hair Growth Promoting Activity of Eclipta Alba in Male Albino Rats Archives of Dermatological Research · 2008
    3. Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia Biological & Pharmaceutical Bulletin · 2006
    4. Finasteride in the Treatment of Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2004
    5. Androgens and Alopecia Molecular and Cellular Endocrinology · 2002
    6. 5α-Reductase Activity in the Prostate Urology · 2001
    7. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    8. Topical Finasteride in the Treatment of Androgenic Alopecia: Preliminary Evaluations After a 16-Month Therapy Course Journal of Dermatological Treatment · 1997
    9. Animal Models of Androgen-Dependent Disorders of the Pilosebaceous Apparatus Archives of dermatological research · 1989

    Related research 2

    1. Effect of Petroleum Ether and Ethanol Fractions of Seeds of Abrus Precatorius on Androgenic Alopecia Revista Brasileira de Farmacognosia · 2011
    2. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992