Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages

April 2023 in “ Stem Cell Research & Therapy ”

Jia Dong, Bin Wu, Weidong Tian

human adipose tissue-derived small extracellular vesicles h-sEV-AT adipogenesis angiogenesis adipose tissue regeneration skin wound healing M2 macrophages adipose-derived stromal/stem cells endothelial cells macrophage polarization fat-derived vesicles fat tissue regeneration wound healing stem cells blood vessel formation

Studysummary This study found that small extracellular vesicles derived from human adipose tissue could promote soft tissue regeneration and increase M2 macrophage polarization, suggesting a promising cell-free approach to tissue repair.

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