Image

    New Drug Targets and Research Methods for Androgenetic Alopecia

    January 2009 in “ Folia Pharmacologica Japonica ”
    Hisaharu Yamada, Akiko Ikeda
    Studysummary This review covers potential molecular targets for androgenetic alopecia treatments but presents no new experimental findings; the authors highlight various in vitro and in vivo screening methods for therapeutic compounds.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jstage.jst.go.jp →
    Discuss this study in the Community →

    Research cited in this study 14

    1. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    2. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006
    3. Biology of the Hair Follicle: The Basics Seminars in Cutaneous Medicine and Surgery · 2006
    4. Androgen-Inducible TGF-β1 from Balding Dermal Papilla Cells Inhibits Epithelial Cell Growth: A Clue to Understanding Paradoxical Effects of Androgen on Human Hair Growth ˜The œFASEB journal · 2002
    5. Hair Growth Effect of Minoxidil Folia Pharmacologica Japonica · 2002
    6. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001
    7. Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways Proceedings of the National Academy of Sciences of the United States of America · 2000
    8. Local Injection of Hepatocyte Growth Factor/Scatter Factor Alters Cyclic Growth of Murine Hair Follicles Journal of Investigative Dermatology · 1998
    9. The Effects of Finasteride (Proscar) on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques (Macaca Arctoides) The Journal of Clinical Endocrinology and Metabolism · 1994
    10. Soluble Factors From Human Hair Papilla Cells And Dermal Fibroblasts Dramatically Increase The Clonal Growth Of Outer Root Sheath Cells Archives of Dermatological Research · 1993
    11. Rat Hair Follicle Growth In Vitro British Journal of Dermatology · 1992
    12. Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque The Journal of Clinical Endocrinology and Metabolism · 1992
    13. Action of Topical Minoxidil in the Bald Stump-Tailed Macaque Journal of The American Academy of Dermatology · 1987
    14. Growth of the Hair Physiological Reviews · 1954