Integrated Evaluation of Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Across Skin-Related Cellular and Zebrafish Models
September 2026
in “
Frontiers in Bioengineering and Biotechnology
”
umbilical cord mesenchymal stromal cells extracellular vesicles UC-MSC-EVs keratinocytes fibroblasts sebocytes melanocytes dermal papilla cells hair growth factor oxidative stress UVB-induced damage cellular senescence lipid accumulation androgen activity melanin content tyrosinase activity umbilical cord stem cells EVs skin cells hair cells UV damage skin aging oil production male hormones skin pigment skin enzyme
Studysummary This study found that human umbilical cord mesenchymal stromal cell-derived extracellular vesicles improved several skin-related processes, including reducing oxidative injury, enhancing wound repair, and modulating androgen-related responses, in various cellular and zebrafish models.
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