Thymosin Beta 4 Induces Hair Growth Via Stem Cell Migration And Differentiation

    September 2007 in “ Annals of the New York Academy of Sciences ”
    Deborah Philp, Sharleen St‐Surin, HEE‐JAE CHA, Hye‐Sung Moon, Hynda K. Kleinman, Michael Elkin
    The study found that thymosin beta 4, a 43-amino-acid molecule, promoted hair growth in various rat and mice models, including a transgenic mouse overexpressing thymosin beta 4. The mechanism by which thymosin beta 4 facilitated hair growth involved the promotion of follicle stem cell growth, migration, differentiation, and protease production. These findings suggested that thymosin beta 4 played a significant role in hair growth through its influence on stem cell activities.
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