Research Advances in Therapeutic Strategies and Drug Delivery Systems for Pathological Scars

    January 2026 in “ Pharmaceutics ”
    Yuxin Shi, Ling Li
    Studysummary This review reports that biomaterial-based drug delivery systems show promise in overcoming the limitations of traditional therapies for pathological scars by integrating sustained drug release with minimally invasive transdermal technologies, potentially enhancing treatment efficacy for these challenging skin lesions.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 10

    1. Regenerative Medicine in the Treatment of Specific Dermatologic Disorders: A Systematic Review of Randomized Controlled Clinical Trials Stem cell research & therapy · 2024
    2. Targeting Wnt/β-Catenin Signaling and Its Interplay with TGF-β and Notch Signaling Pathways for the Treatment of Chronic Wounds Cell Communication and Signaling · 2024
    3. Pharmacotherapy for Keloids and Hypertrophic Scars International journal of molecular sciences · 2024
    4. Cocktail Cell-Reprogrammed Hydrogel Microspheres Achieving Scarless Hair Follicle Regeneration Advanced Science · 2024
    5. Nano Drug Delivery Systems: A Promising Approach to Scar Prevention and Treatment Journal of Nanobiotechnology · 2023
    6. WNT5A Drives Interleukin-6-Dependent Epithelial-Mesenchymal Transition via the JAK/STAT Pathway in Keloid Pathogenesis Burns & Trauma · 2022
    7. Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors to Improve Skin Regeneration ACS Applied Bio Materials · 2019
    8. Wound Healing: A Cellular Perspective Physiological Reviews · 2018
    9. Recent Understandings of Biology, Prophylaxis, and Treatment Strategies for Hypertrophic Scars and Keloids International journal of molecular sciences · 2018
    10. Cutaneous Wound Healing: Recruiting Developmental Pathways for Regeneration Cellular and Molecular Life Sciences · 2012