The importance and use of stem cells in dermatology

January 2016 in “ Dermatology Review ”

Agnieszka Owczarczyk‐Saczonek, Waldemar Placek, Wojciech Maksymowicz

stem cells interfollicular stem cells follicular stem cells mesenchymal stem cells melanocyte stem cells dystrophic epidermolysis bullosa systemic lupus erythematosus vitiligo alopecia ulcers regenerative medicine

TLDR Stem cells show promise for treating skin conditions and aiding healing.

Stem cells in dermatology were recognized for their ability to self-renew and differentiate into specialized cells, with various niches identified in the skin, including interfollicular, follicular, mesenchymal, and melanocyte stem cells. Although treatment of skin diseases with stem cells was still experimental, research focused on their potential in treating conditions like dystrophic epidermolysis bullosa, systemic lupus erythematosus, vitiligo, various types of alopecia, ulcers, and slow-healing wounds. Their flexibility and differentiation capabilities offered promising possibilities for regenerative medicine.

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The importance and use of stem cells in dermatology

Research cited in this study

research Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration

research The Use of Stem Cells in Plastic and Reconstructive Surgery

research Hair Organ Regeneration Via Bioengineered Hair Follicular Unit Transplantation

research In Vitro Differences Between Keratinocyte Stem Cells and Transit-Amplifying Cells of the Human Hair Follicle

research Long-Term Follow-Up of Leucoderma Patients Treated with Transplants of Autologous Cultured Melanocytes, Ultrathin Epidermal Sheets, and Basal Cell Layer Suspension

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