Influence of Surface Functional Groups on the Hair Growth-Promoting Activities of Nanochitins: An In Vitro Analysis

November 2025 in “ Biomacromolecules ”

Chunsheng Fu, Lihua Chen, Liang Liu, Xingyu Yi, Yimin Fan, Yishan Wang, Chen Shen, Min Sha, Chunyu Cao, Chunsheng Fu, Lihua Chen, Liang Liu, Xingyu Yi, Yimin Fan, Yishan Wang, Chen Shen, Min Sha, Chunyu Cao

nanochitin partially deacetylated nanochitin hydrochloric acid hydrolyzed nanochitin phosphoric acid hydrolyzed nanochitin amphoteric nanochitin VEGF FGF-7 angiogenesis dermal repair DNCh HNCh PNCh ANCh vascular endothelial growth factor fibroblast growth factor 7

Studysummary This research found that four types of biocompatible nanochitin promoted hair growth in mice, with partially deacetylated and phosphoric acid hydrolyzed nanochitins showing the best results, while amphoteric nanochitin provided the most balanced overall effect.

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