Shock: A Possible Presenting Manifestation of Autoimmune Polyendocrine Syndrome Type II
January 2014
in “
Indian Journal of Critical Care Medicine
”
Studysummary This report describes a 38-year-old female diagnosed with autoimmune polyendocrine syndrome Type II after presenting with shock.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
A 38-year-old female presented in shock and was diagnosed with Autoimmune Polyendocrine Syndrome Type II (APS II), characterized by multiple endocrine insufficiencies including Addison's disease, hypothyroidism, and primary ovarian failure. Initial treatment with intravenous fluids, antibiotics, and dopamine was ineffective, but she improved with intravenous hydrocortisone and oral L-thyroxine. She was discharged after 1 week on a regimen of oral prednisolone, fludrocortisone, L-thyroxine, estrogen, and progesterone, which normalized her clinical condition and reduced skin pigmentation. The case highlighted the importance of early identification and treatment of associated autoimmune endocrine diseases.
