Autoimmune Polyglandular Syndrome Type 4 – Case Report

January 2019 in “ Przegląd Dermatologiczny ”

Agata Liszewska, Ewa Robak, Małgorzata Bernacka, Anna Woźniacka, Jarosław Bogaczewicz

autoimmune polyglandular syndrome type 4 generalized alopecia rheumatoid arthritis antithyroid microsomal antibodies sulfasalazine methotrexate methylprednisolone APS-4 hair loss RA antithyroid antibodies Azulfidine Trexall Medrol

TLDR Patients with one autoimmune disease should be checked for other autoimmune disorders.

A case report described a 57-year-old woman with autoimmune polyglandular syndrome type 4 (APS-4), generalized alopecia, and rheumatoid arthritis. She had a 4-year history of leg ulcers and exhibited loss of eyebrows, eyelashes, scalp hair, and axillary hair. Antithyroid microsomal antibodies were detected in her serum. Over the past 15 years, she had been treated with sulfasalazine, methotrexate, and methylprednisolone for rheumatoid arthritis. The report concluded that patients with a single organ-specific autoimmune disease should be evaluated for other coexisting autoimmune disorders.

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