Effects of Scalp Lotion Containing Alpha Lipoic Acid Derivatives for Chemotherapy-Induced Alopecia in Patients with Gastrointestinal Cancer: A Prospective Cohort Study

    Takahiro Hiratsuka, Yohei Kono, Chiho Tomimatsu … Masafumi Inomata
    Studysummary This study found that a lotion containing an alpha lipoic acid derivative increased hair diameter in chemotherapy patients with gastric or colorectal cancer, while those not using the lotion had more pronounced hair loss, suggesting potential benefits in managing chemotherapy-induced alopecia.
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    Research cited in this study 6

    1. The Utility of DHL-HisZnNa, a Novel Antioxidant, Against Anticancer Agent-Induced Alopecia in Breast Cancer Patients: A Multicenter Phase II Clinical Trial Breast Cancer Research and Treatment · 2019
    2. A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention Oncologist · 2017
    3. Hair Shaft Abnormalities After Chemotherapy and Tamoxifen Therapy in Patients With Breast Cancer Evaluated by Optical Coherence Tomography British Journal of Dermatology · 2012
    4. The Alpha-Lipoic Acid Derivative Sodium Zinc Dihydrolipoylhistidinate Reduces Chemotherapy-Induced Alopecia in a Rat Model: A Pilot Study Surgery today · 2011
    5. Hair Cycle and Hair Pigmentation: Dynamic Interactions and Changes Associated with Aging Micron · 2003
    6. A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia Journal of The American Academy of Dermatology · 1996