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    A Matter of Life and Death: Self-Renewal in Stem Cells

    December 2012 in “ EMBO Reports ”
    Elaine Fuchs, Ting Chen
    Studysummary This review explores the mechanisms of adult stem cell self-renewal, using skin as a model, and reports no new results but raises important unanswered questions in the field.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 8

    1. Identification of Stem Cell Populations in Sweat Glands and Ducts Reveals Roles in Homeostasis and Wound Repair Cell · 2012
    2. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    3. Distinct Stem Cells Contribute to Mammary Gland Development and Maintenance Nature · 2011
    4. EZH1 and EZH2 Co-Govern Histone H3K27 Trimethylation and Are Essential for Hair Follicle Homeostasis and Wound Repair Genes & Development · 2011
    5. Tracking Adult Stem Cells EMBO Reports · 2011
    6. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    7. Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells Nature Genetics · 2008
    8. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007