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    Exogenous IGF-1 Promotes Hair Growth by Stimulating Cell Proliferation and Downregulating TGF-β1 in C57BL/6 Mice In Vivo

    March 2014 in “ Growth Hormone & IGF Research ”
    Jingjie Li, Zhihong Yang, Zheng Li … Chang‐Keun Sung
    Studysummary This study found that IGF-1 injections increased hair follicle number and growth phase duration in wild-type mice, suggesting potential for baldness treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. Ginsenosides Rb1 and Rd Regulate Proliferation of Mature Keratinocytes Through Induction of p63 Expression in Hair Follicles PTR. Phytotherapy research/Phytotherapy research · 2012
    2. Overexpression of mIGF-1 in Keratinocytes Improves Wound Healing and Accelerates Hair Follicle Formation and Cycling in Mice American Journal Of Pathology · 2008
    3. Developmental Timing of Hair Follicle and Dorsal Skin Innervation in Mice Journal of comparative neurology · 2002
    4. Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1 ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1999
    5. Overexpression of Insulin-Like Growth Factor-1 Induces Hyperplasia, Dermal Abnormalities, and Spontaneous Tumor Formation in Transgenic Mice Oncogene · 1997
    6. Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy Molecular Medicine Today · 1996
    7. Human Hair Growth In Vitro: A Model for the Study of Hair Follicle Biology Journal of Dermatological Science · 1994
    8. Human Hair Growth In Vitro Journal of Cell Science · 1990
    9. Growth of the Hair Physiological Reviews · 1954