Photobiomodulation for the management of hair loss

Photobiomodulation (PBM), also known as low-level laser therapy (LLLT), was explored as a treatment for hair loss, showing promise in increasing hair density and thickness, particularly in androgenetic alopecia (AGA). Devices like the HairMax LaserComb and Capillus Laser Therapy Cap received FDA clearance for pattern hair loss, with studies showing significant improvements, such as a 19.8 hairs/cm² increase in hair density in 110 males and a 51% increase in terminal hair counts in 44 females. PBM also showed potential benefits for alopecia areata (AA) and lichen planopilaris (LPP), though no devices were FDA-approved for these conditions. Despite its effectiveness, the high cost of PBM devices and lack of standardized protocols were noted as limitations, and further large-scale studies were needed to confirm efficacy and establish optimal treatment protocols.