Hyperbranched Glycerol-Based Core-Amphiphilic Branched Shell Nanotransporters for Dermal Drug Delivery
May 2016
in “
Polymer
”
nanocarriers glycerol-based hyperbranched core amphiphilic branched shell dermal drug delivery hyperbranched polymers hydrophobic C18 alkyl chain solubility pyrene dexamethasone finasteride critical micelle concentrations cytotoxicity human keratinocyte cells skin penetration Nile red base cream glycerol-based core branched shell skin drug delivery polymers C18 alkyl chain Propecia micelle concentrations toxicity skin cells
Studysummary This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.
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