Histopathologic Findings of Cutaneous Hyperpigmentation in Addison's Disease and Immunostain of the Melanocytic Population
cutaneous hyperpigmentation Addison disease female pattern alopecia basal melanin hyperpigmentation melanophages papillary dermis lipofuscin eccrine glands Perls-positive pigment macrophages melanocyte/keratinocyte ratio skin darkening Addison's disease female hair loss melanin skin cells sweat glands iron pigment immune cells skin cell ratio
Studysummary This study examined skin biopsies from a woman with Addison disease and found melanocytic hyperpigmentation in the epidermis, with a notable melanocyte/keratinocyte ratio indicating increased melanocyte presence in the arm compared to the thigh.
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