TLDR A man developed myasthenia gravis after alopecia areata, and treatment improved his symptoms and stopped hair loss.
A 41-year-old male developed myasthenia gravis (MG) following alopecia areata (AA), with symptoms including hair loss, drooping eyelids, and double vision. Treatment with prednisolone and tacrolimus improved his MG symptoms and halted further hair loss. A literature review identified 29 cases of AA and MG comorbidity, with MG typically developing an average of 16.6 months after AA. Some cases also had other autoimmune diseases, indicating a potential Th1-dominant immunological involvement.
16 citations,
January 2022 in “International journal of molecular sciences” Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.
10 citations,
May 2019 in “Internal Medicine” Myasthenia gravis can affect both motor and non-motor systems due to immune system issues.
31 citations,
September 2011 in “Journal of the neurological sciences” Removing the thymoma improved the man's autoimmune conditions.
1 citations,
August 2023 in “Acta dermato-venereologica” Corticosteroids are the most common treatment for alopecia areata, but many patients need better options.
6 citations,
December 2022 in “Journal of autoimmunity” JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
October 2022 in “Journal of Armed Forces Medical College, Bangladesh” Tofacitinib is effective and safe for treating alopecia areata.
39 citations,
April 2016 in “Case Reports in Dermatology” Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.
5 citations,
June 2015 in “Veterinary dermatology” A dog with complete hair loss regrew most hair after treatment, with no relapse after stopping treatment.
39 citations,
April 2003 in “Australasian journal of dermatology” PUVA treatment led to significant hair regrowth in over half of the patients with alopecia areata totalis and universalis.