Macrophage-Derived Extracellular Vesicle Promotes Hair Growth
April 2020
in “Cells”
TLDR Special cell particles from macrophages can help hair grow.
In 2020, researchers studied the role of macrophage-derived extracellular vesicles (MAC-EVs) in promoting hair growth. The study found that MAC-EVs, which contain proteins Wnt3a and Wnt7b, can stimulate hair growth by activating the Wnt/β-catenin signaling pathway, a key pathway involved in hair follicle development. The MAC-EVs were applied to the skin of mice and human hair follicles, resulting in a significant increase in hair growth, hair follicle numbers, and dermis thickness. The MAC-EVs also enhanced the proliferation, migration, and levels of hair-inductive markers of dermal papilla (DP) cells. These findings suggest that MAC-EVs could potentially be used as a treatment for hair loss conditions such as alopecia.
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