Jak Inhibitors in Down Syndrome: Alopecia Areata Resolution and Vitiligo Improvement with Baricitinib

    September 2025 in “ Acta Dermato Venereologica ”
    Federica Li Pomi, Mario Vaccaro, Maria Giuseppa Vitale … Francesco Borgia
    Studysummary Baricitinib can help improve hair loss and skin color issues in people with Down syndrome.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 6

    1. JAK Inhibition Decreases the Autoimmune Burden in Down Syndrome eLife · 2024
    2. Down Syndrome and Autoimmune Disease Clinical Reviews in Allergy & Immunology · 2024
    3. Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences International journal of molecular sciences · 2024
    4. Two Phase 3 Trials of Baricitinib for Alopecia Areata The New England Journal of Medicine · 2022
    5. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    6. Janus Kinase Inhibition in Down Syndrome: Two Cases of Therapeutic Benefit for Alopecia Areata JAAD case reports · 2019

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    1. Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child International journal of research in dermatology · 2019