Down Syndrome and Autoimmune Disease

    Brian Hom, Natalie K. Boyd, Benjamin N. Vogel … Jonathan D. Santoro
    Studysummary This review highlights a higher prevalence of autoimmune disorders such as thyroid disease, celiac disease, alopecia areata, and vitiligo among individuals with Down syndrome compared to the neurotypical population, suggesting intrinsic immune dysregulation linked to chromosome 21.
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    Research cited in this study 5

    1. Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management Clinical Reviews in Allergy & Immunology · 2021
    2. Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options Clinical and Experimental Medicine · 2021
    3. Treatment of Alopecia Areata: An Australian Expert Consensus Statement Australasian journal of dermatology · 2018
    4. Alopecia Areata: A Review of Disease Pathogenesis British journal of dermatology/British journal of dermatology, Supplement · 2018
    5. Alopecia Areata: Overview and Insights from January 2018 Journal of The American Academy of Dermatology · 2017