The Trilogy of Skin Regeneration via Metal-Organic Frameworks Nanomedicine: Precision Management of Refractory Wounds, Pathological Scarring, and Hair Follicle Reactivation

    August 2025 in “ International Journal of Nanomedicine ”
    Lv Xiong, Chun Xiang, Yan Zheng … Wan-Xuan Zhou
    Studysummary This review discusses metal-organic frameworks for treating diabetic infected wounds and related applications, reporting no new clinical results but highlighting challenges like biosafety and production for future research.
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    Research cited in this study 6

    1. Modulating Metal-Organic Frameworks by Surface Engineering of Stearic Acid Modification for Follicular Drug Delivery and Enhanced Hair Growth Promotion Journal of Nanobiotechnology · 2025
    2. Dual-Continuous Microneedle Patch Integrating Transdermal Delivery of pH-Sensitive Licorzinc MOFs and Zn2+ Hydrogel Sensors for Treating Alopecia Areata Chemical Engineering Journal · 2024
    3. Synergistic Treatment of Androgenetic Alopecia with Follicular Co-Delivery of Minoxidil and Cedrol in Metal-Organic Frameworks Stabilized by Covalently Cross-Linked Cyclodextrins International Journal of Pharmaceutics · 2024
    4. Neuro-Inspired Biomimetic Microreactor for Sensory Recovery and Hair Follicle Neogenesis Under Skin Burns ACS Nano · 2023
    5. Curcumin-Zinc Framework Encapsulated Microneedle Patch for Promoting Hair Growth Theranostics · 2023
    6. 3D Spheroid Human Dermal Papilla Cell as an Effective Model for the Screening of Hair Growth Promoting Compounds: Examples of Minoxidil and 3,4,5-Tri-O-Caffeoylquinic Acid (TCQA) Cells · 2022

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