Influences of IGF-1 and EGF on Primary Hair Follicles of Liaoning Cashmere Goat In Vitro
January 2010
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Shenyang Nongye Daxue xuebao
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research Effects of IGF-I and EGF on in vitro growth of hair follicles of sheep
The study investigated the effects of IGF-I and EGF on sheep hair follicles cultured in vitro. It was found that 10 ng/mL IGF-I and 20 ng/mL EGF both stimulated hair follicle growth. IGF-I positively regulated follicle growth, while 20 ng/mL EGF accelerated the differentiation of external root sheath cells and induced an earlier transition from the growing to the recessing period. The combination of 10 ng/mL IGF-I and 20 ng/mL EGF further accelerated hair follicle growth.