Influences of IGF-1 and EGF on Primary Hair Follicles of Liaoning Cashmere Goat In Vitro

January 2010 in “ Shenyang Nongye Daxue xuebao ”

Yao Y, Liu Haiying, Ying Yuan, Yuyan Cong

IGF-1 insulin-like growth factor 1 EGF epidermal growth factor dermal papilla matrix cells outer root sheath cells hair bulbs hair follicle growth

TLDR IGF-1 and EGF together significantly boost hair follicle growth in cashmere goats.

The study investigated the effects of IGF-1 and EGF on the growth and morphology of primary hair follicles from Liaoning cashmere goats in vitro. It was found that IGF-1 promoted the proliferation of dermal papilla and matrix cells, while EGF regulated the differentiation of outer root sheath cells. The combination of IGF-1 and EGF stimulated the formation of larger hair bulbs. The optimal concentrations for promoting follicle growth were 10 ng/mL for IGF-1 and 20 ng/mL for EGF. The combined supplementation of IGF-1 and EGF significantly enhanced hair follicle growth compared to using either factor alone.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 11 months ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community Trichotest results in… min not on my list! Just Fin/Dut, Zinc… and the insanely expensive latanoprost & prostaquinon.

in Technology 22 upvotes 3 years ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 2 months ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )

in Treatment 6 upvotes 8 months ago

The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.

community Serum based on plant extracts boosts hair growth in weeks.

in Treatment 44 upvotes 1 month ago

A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

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